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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RARA All Species: 6.67
Human Site: S424 Identified Species: 14.67
UniProt: P10276 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10276 NP_000955.1 462 50771 S424 S E G L D T L S G Q P G G G G
Chimpanzee Pan troglodytes XP_001164332 455 50471 I410 P G S M P P L I Q E M L E N S
Rhesus Macaque Macaca mulatta XP_001092337 458 50660 I413 P G S M P P L I Q E M L E N S
Dog Lupus familis XP_850755 448 50317 I403 P G S M P P L I Q E M L E N S
Cat Felis silvestris
Mouse Mus musculus P11416 462 50717 S424 S E G L D T L S G Q S G G G T
Rat Rattus norvegicus P63059 492 55053 R414 V V Q G P Q V R Q L E Q Q F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505930 454 50143 I409 P G S M P P L I Q E M L E N S
Chicken Gallus gallus Q90966 460 50710 G424 S E G M D T L G G Q P G G P R
Frog Xenopus laevis P51126 458 50544 G424 E G L D T L G G G A S S D A P
Zebra Danio Brachydanio rerio Q90271 444 49906 S411 S E G L E S S S G A Q G S R A
Tiger Blowfish Takifugu rubipres Q9W5Z3 447 49514 L412 M L E N S E G L E S G A T G S
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77 74 72.5 N.A. 98.2 34.3 N.A. 72.2 94.1 86.1 78.3 83.9 N.A. N.A. N.A. N.A.
Protein Similarity: 100 84.1 82 79.8 N.A. 99.1 50.4 N.A. 81.5 96.5 91.3 85.9 90 N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 86.6 6.6 N.A. 6.6 73.3 6.6 46.6 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 20 20 N.A. 86.6 13.3 N.A. 20 80 6.6 60 6.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 19 0 10 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 28 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 10 37 10 0 10 10 0 0 10 37 10 0 37 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 46 37 10 0 0 19 19 46 0 10 37 28 28 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 10 28 0 10 64 10 0 10 0 37 0 0 0 % L
% Met: 10 0 0 46 0 0 0 0 0 0 37 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 37 0 % N
% Pro: 37 0 0 0 46 37 0 0 0 0 19 0 0 10 10 % P
% Gln: 0 0 10 0 0 10 0 0 46 28 10 10 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 10 % R
% Ser: 37 0 37 0 10 10 10 28 0 10 19 10 10 0 46 % S
% Thr: 0 0 0 0 10 28 0 0 0 0 0 0 10 0 10 % T
% Val: 10 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _